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Additionally, their levels of HDL (good) cholesterol rose by an average of 6%. HDL is an important factor in the risk of heart conditions, including atherosclerosis ( 18).
Bongers CCWG, Ten Haaf DSM, Catoire M, et al. Effectiveness of collagen supplementation on pain scores in healthy individuals with self-reported knee pain: a randomized controlled trial. Appl Physiol Nutr Metab. 2020;45(7):793-800. doi:10.1139/apnm-2019-0654 Periodontitis is a highly prevalent disease among adults that is usually triggered by a bacterial infection and it affects the tissues surrounding the dentition. If left untreated, it can lead to loss of teeth. The use of different biomaterials in periodontal regeneration has been studied for years. Several treatment options for periodontal disease include open flap debridement (OFD), biologically active regenerative materials, bone-replacement graft materials, scaling and root planning, and guided tissue regeneration with barrier membranes [ 87, 88, 89, 90, 91, 92]. The combined use of barrier membranes and biomaterials was shown to be more effective than using OFD alone. Collagen from either human or animal tissue was widely used as natural resorbable barrier membranes and the resorption of collagen membranes depended on the source of the material (bovine, porcine, human) [ 93]. Digestive enzymes break down the collagen in food into individual amino acids and peptides. However, the collagen in supplements has already been broken down, or hydrolyzed, which is why it’s thought to be absorbed more efficiently than collagen from foods. Summary
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Nevertheless, more studies on collagen supplements and heart health are needed. 6. Other health benefits
Vital Proteins products are made in an NSF-certified, Current Good Manufacturing Practices (CGMP)-compliant facility and are free of: Some nutritionists are positive about collagen supplements though. “Normally as a nutritionist I would recommend food first over supplements, but collagen is an exception because most of the studies that suggest a benefit have been done with supplements rather than food”, says nutritionist Fiona Hunter. She adds that supplements might “offer collagen in a form that is easier for the body to absorb.”While there is research to suggest collagen supplements could benefit your skin, more studies are needed to get a definitive answer. Dr Mahto doesn’t believe collagen supplements will be harmful, especially in the doses available. Even though the research is promising, experts caution that stronger evidence is still needed before recommending collagen as a treatment for osteoarthritis. 3. May prevent bone loss It’s made with collagen peptides, sometimes called hydrolyzed collagen, which have been broken down into smaller compounds that are easier for your body to absorb.
From the above discussions, compared with other drugs, collagen treatment has many advantages. However, it does not mean that the collagen treatment is absolutely safe. Some people may have an allergic reaction to collagen treatment. For example, some people may have a shellfish allergy and could experience anaphylaxis if they take marine collagen supplements. The other source of collagen may have an allergy problem. Collagen has porcine and bovine origins that cow and pig skins and bones are the main sources of collagen. However, due to religious constraints concerning the avoidance of porcine and bovine products or other reasons such as the outbreak of BSE, the marine collagen source is being highly considered by the industry as an important alternative [ 11, 36, 37]. Marine collagens have the advantages of a high yield and no disease transmission risk that can be obtained from invertebrate marine animals or fishes. Mammalian collagens have higher thermal stability than fish collagens due to the lower imino acid contents of fish collagens compared with mammalian collagens [ 38]. The thermal stability is related to body temperature and living environment and the low thermal stability of marine collagens restricts its applications [ 39]. The mechanical strength of marine collagen is poorer than collagen extracted from bovine because it is less crosslinked. After the crosslinking treatment, marine collagen can be used as a biomaterial in tissue engineering [ 40]. Despite some limitations, the marine collagen is an appealing option for product developers because the source is cheap and no risk of BSE. In the latest 20 years, more than 175 chemical entities and 28 marine natural products were discovered. Marine organisms, as well as their wastes, are good sources of collagen for many applications [ 41, 42, 43, 44, 45].
Collagen is most commonly derived from bovine, porcine, or marine sources. It can also be produced synthetically from insect, yeast, and plant or mammal cultures, resulting in a lower risk of allergic reactions. This type is found in bones, ligaments, tendons and skin for elasticity and strength. The supplement source comes from bovine and fish. Martínez-Puig D, Costa-Larrión E, Rubio-Rodríguez N, et al. Collagen supplementation for joint health: the link between composition and scientific knowledge. Nutrients. 2023;15(6):1332. Published 2023 Mar 8. doi:10.3390/nu15061332
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